Cheap Flights from Santiago to Medellin

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Flight deals from Santiago to Medellin

Looking for a cheap last-minute deal or the best return flight from Santiago to Medellin? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Santiago to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santiago to Medellin flights are currently cheapest in June.

Alternative Santiago to Medellin routes

Looking for the cheapest, fastest or easiest route from Santiago to Medellin? You could fly into the following airports instead.

Santiago to Medellin: Flight information

The things to know before you go.
Cheapest flight foundRs69,634
Cheapest month to flyJune

Finding cheap flights from Santiago to Medellin: Frequently asked questions

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.
The best price we found for a return flight from Santiago to Medellin is Rs160,681. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Santiago to Medellin. But we found flights with one or more stops from Rs160,681.
As of May 2025, there are no flights flying from Santiago to Medellin.
The cheapest month to fly from Santiago to Medellin is usually May 2025.
If you're flying from Santiago Airport, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 18.9 km away from the centre of Medellin. We've found flights into this airport from Rs160,681.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Santiago Airport to Medellin on Monday, 30 June 2025.
No airlines currently offer direct flights between Santiago Airport and Medellin. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 18°C. May is typically the warmest month in Medellin, when it usually averages around 21°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 15°C. The rainiest month is May.
Currently, Frontier Airlines offers the cheapest flight tickets to Medellin.

Travelling from Cibao International Airport (STI) to Medellin: what you need to know

  • Cibao International Airport is located in Santiago. Based in the UTC-5 timezone, Medellin is one hour behind Santiago.

  • Give yourself enough time to make your STI to Medellin flight. It's generally best to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • If you're travelling during a bank holiday or another peak period, give yourself extra time. A good general rule is two hours before domestic flights and up to four hours before international departures. Queues at security and check-in will be longer.

  • Think about adding a stopover to potentially score a cheaper flight ticket from STI to Medellin. Simply uncheck 'Direct flights only' during your search. Give yourself a breather (and maybe even a better deal) by stopping at one of these popular airports:

    • Miami International Airport (MIA)

    • Tocumen International Airport (PTY)

    • Luis Munoz Marin International Airport (SJU)

  • STI is about 13 kilometres from central Santiago. If you're driving, ride-sharing or catching a cab from the centre, it'll take you 30 minutes or so to get there, depending on traffic conditions. If you're taking public transport, expect the travel time to be around 1 hour 10 minutes.

  • Searching for a hotel near STI? If you're boarding an early flight from Cibao International Airport to Medellin, these accommodation options will put you moments from check-in:

  • Of the flights that depart from Cibao International Airport, 73.05% arrive on time at their destination.

How to find the cheapest flights from Cibao International Airport (STI) to Medellin

  • Rs69,634 is the cheapest price we've seen for a one-way Cibao International Airport to Medellin flight. A round-trip flight ticket right now is Rs160,681. Depending on when and how early you book, these fares may change.

  • To find cheap flights from STI to Medellin, book as early as you can. Airlines typically offer their most competitively priced fares when flights first go on sale.

  • If you're willing to be flexible with your travel plans, try using the 'Whole month' tool. It'll show you the cheapest price across every month when searching for a Cibao International Airport to Medellin ticket.

  • Stay on top of deals for cheap flights from STI to Medellin by setting up a Price Alert. You'll get an email or notification on the app when a lower fare pops up.

  • Save on your flight from Cibao International Airport to Medellin with the help of our filters. Choose your ideal times, number of stops and airlines, then sort the results by 'Cheapest' to see the best deals.

Airports in Medellin

Jose Maria Cordova International Airport (MDE)

  • The distance from Jose Maria Cordova International Airport (MDE) to central Medellin is roughly 24 kilometres. It takes around 35 minutes to get to the centre driving.

  • Book a hotel close to MDE if you have a late flight from Cibao International Airport to Medellin. Settle into one of these accommodation options and make arrival day easier:

  • Pick up a Jose Maria Cordova International Airport rental car and discover Medellin and beyond with your own wheels. Localiza, Green Motion and Confort Rent a Car are leading providers you can book with here.

  • Booking your vehicle from Jose Maria Cordova International Airport around one week before your flight from STI to Medellin can help you get the lowest rate.

Enrique Olaya Herrera Airport (EOH)

  • Once your flight from Cibao International Airport to Medellin has hit the runway, you can reach the city centre in about 15 minutes by car. Central Medellin is roughly 6 kilometres from Enrique Olaya Herrera Airport (EOH).

  • You can expect the trip to take about 30 minutes on public transport.

  • Following your STI to Medellin flight, kick back at a hotel near EOH. These are some comfortable options that'll help you sink into relaxation mode:

  • Land, collect your Enrique Olaya Herrera Airport rental car, and hit the road without skipping a beat. Confort Rent a Car and Green Motion are well-known companies to pick from here.

  • Avoid paying extra. Securing your ride one week before your arrival at EOH can land you a better rate.

Best time to go to Medellin

  • Visit Medellin during the high season if you like a bustling atmosphere, but remember that prices are generally higher. Alternatively, book flights from Cibao International Airport to Medellin during low season when prices are cheaper and it's quieter.

  • The warmest month in Medellin is August, with temperatures ranging between 11ºC and 27ºC. Lock in your Cibao International Airport to Medellin flight ticket then if that's the weather you find most pleasant.

  • If you'd rather travel in cooler conditions, look for a cheap ticket from STI to Medellin in July when temperatures average between 11ºC and 27ºC.

More about Medellin

  • Once you've booked your flight from Cibao International Airport to Medellin, choose a hotel that puts you where you want to be. Make one of these accommodation options your base for exploring Medellin:

  • There are so many things to do and see in this city it can be hard to figure out where to start. Botero Plaza, Parque Arvi and Pueblito Paisa are leading attractions which should feature on any well-planned Medellin itinerary.

Explore more of Colombia

  • You've seen Medellin, now it's time to discover other corners of Colombia. Journey about 241 kilometres south-east to Bogota to check off its top attractions. From Gold Museum to Usaquen Train Station and Urbanización Villas del Madrigal - Molino del Viento Park, you'll have a packed itinerary ahead.

  • Around 322 kilometres south of Medellin, Cali is another essential stop in Colombia. Get a taste of what this destination has to offer at Cristo Rey, Gato de Tejada and Caliwood Museo de la Cinematografia.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.