Cheap Flights from Santo Domingo to Guayaquil

Compare Santo Domingo to Guayaquil flight deals

Find the cheapest month or even day of the year to fly to Guayaquil

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Flight deals from Santo Domingo to Guayaquil

Looking for a cheap last-minute deal or the best return flight from Santo Domingo to Guayaquil? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Santo Domingo to Guayaquil

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santo Domingo to Guayaquil flights are currently cheapest in November.

Santo Domingo to Guayaquil: Alternative routes

Compare routes from Santo Domingo to Guayaquil below. You may find an airport to fly into that's cheaper, faster, or easier than Guayaquil.

Santo Domingo to Guayaquil: Flight information

The things to know before you go.
Cheapest flight foundRs52,950
Cheapest month to flyNovember

Finding cheap flights from Santo Domingo to Guayaquil: Frequently asked questions

The best price we found for a return flight from Santo Domingo to Guayaquil is Rs113,815. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Santo Domingo to Guayaquil. But we found flights with one stop from Rs113,815.
As of July 2025, there are no flights flying from Santo Domingo to Guayaquil.
The cheapest month to fly from Santo Domingo to Guayaquil is usually August.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santo Domingo to Guayaquil Airport on Tuesday, 19 August 2025.
No airlines currently offer direct flights between Santo Domingo and Guayaquil Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Guayaquil but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Guayaquil is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Guayaquil is Avianca .

Flying from Santo Domingo to Jose Joaquin de Olmedo Airport (GYE): What you need to know

  • Santo Domingo has two main airports where you can start your adventure. Explore your options for booking a flight from Santo Domingo to Jose Joaquin de Olmedo Airport (GYE) heading out from Las Americas International Airport (SDQ) or Dr. Joaquin Balaguer International Airport (JBQ).

  • Guayaquil is one hour behind Santo Domingo. Jose Joaquin de Olmedo Airport is located in Guayaquil, which operates on the UTC-5 timezone.

  • Get to the airport on time so you don't miss your flight from Santo Domingo to GYE. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid the mad dash to your gate.

  • Longer lines at security and check-in are more likely if you're travelling during high season, so give yourself a little extra breathing room. The recommendation for peak periods? Get there up to four hours ahead for international flights and at least two hours for domestic departures.

Airports in Santo Domingo

Las Americas International Airport (SDQ)

  • Stopovers are the ideal opportunity to break up your journey and maybe even explore a different city. When searching for cheap flights from Santo Domingo to GYE departing from Las Americas International Airport (SDQ), uncheck the 'Direct flights only' box to discover where you can stop along the way. Your journey might pause in:

    • El Dorado International Airport (BOG)

    • Tocumen International Airport (PTY)

    • Mariscal Sucre International Airport (UIO)

  • The distance from central Santo Domingo to SDQ is around 32 kilometres. Depending on traffic conditions, it'll take you about 30 minutes to get there if you're driving, ride-sharing or catching a cab.

  • Planning to catch an early flight from Santo Domingo to Jose Joaquin de Olmedo Airport? Avoid the mad dash to the terminal (and enjoy a little extra shut-eye) by choosing one of these hotels near Las Americas International Airport:

  • When it comes to Las Americas International Airport's on-time performance, data shows 72.45% of flights arrive within the expected time frame.

Dr. Joaquin Balaguer International Airport (JBQ)

  • Driving from central Santo Domingo to JBQ typically takes 25 minutes, depending on traffic. The distance from the city centre to the airport is around 19 kilometres.

  • You're off on holiday, so why not book another night away at a hotel close to Dr. Joaquin Balaguer International Airport? Before your Santo Domingo to GYE flight, make yourself comfortable at Micro Hotel Condo Suites.

About Jose Joaquin de Olmedo Airport (GYE)

  • Consider booking a hotel near GYE if you have a late flight from Santo Domingo to Jose Joaquin de Olmedo Airport. Choose one of these accommodation options and say goodnight sooner:

  • Explore without limits with a Jose Joaquin de Olmedo Airport rental car. Book your wheels from Europcar, Keddy By Europcar or Goldcar and discover more of Guayaquil and beyond.

  • To secure the lowest price, book your vehicle around four weeks ahead of your Santo Domingo to Jose Joaquin de Olmedo Airport flight.

Getting from Jose Joaquin de Olmedo Airport (GYE) to central Guayaquil

  • Jose Joaquin de Olmedo Airport is around 5 kilometres from central Guayaquil. The time it takes to get to the centre in a car hire or cab will depend on the time of day. Do a little research before your trip.

  • It typically takes 20 minutes if you're travelling by public transport.

How to find the cheapest flights from Santo Domingo to Jose Joaquin de Olmedo Airport (GYE)

  • At the moment, Rs52,950 is the lowest price we've found for a one-way ticket from Santo Domingo to Jose Joaquin de Olmedo Airport. The cheapest price for a return flight is Rs113,815. Keep in mind fares can change due to demand at the time of booking.

  • Booking early is often the key to finding a cheap flight from Santo Domingo to GYE. Airlines adjust prices based on demand, so the closer you get to departure, the more it could cost you.

  • If you're flexible with your travel plans, try using the 'Whole month' tool. It'll show you the lowest price across the month when searching for your Santo Domingo to Jose Joaquin de Olmedo Airport ticket.

  • Finding a cheap flight ticket from Santo Domingo to GYE is a piece of cake with Price Alerts. Simply create one of these automatic alerts and we'll notify you as soon as there's a price drop.

  • Find an affordable flight from Santo Domingo to Jose Joaquin de Olmedo Airport by using the search filters. Select your preferred departure time, duration and airlines, then sort the results by 'Cheapest' for the best deals.

The best time to fly from Santo Domingo to Jose Joaquin de Olmedo Airport (GYE)

  • It's time to figure out your travel dates for your flight from Santo Domingo to Jose Joaquin de Olmedo Airport (GYE). August is the busiest month to travel to Guayaquil. If a slower pace sounds more appealing, go in April.

  • Lock in a Santo Domingo to GYE flight ticket departing in November if you're eager to visit the city during its warmest month. Expect temperatures in Guayaquil to range from 19ºC to 33ºC.

  • Search for cheap tickets from Santo Domingo to Jose Joaquin de Olmedo Airport in August if you'd rather travel when it's cooler. Temperatures are at their lowest then, ranging between 19ºC and 31ºC.

More about Guayaquil

  • When it comes to searching for somewhere to rest your head, you'll find the best places to stay in Guayaquil right here. Check out these options after you've booked your flight from Santo Domingo to Jose Joaquin de Olmedo Airport:

  • Amazon Rainforest and Stella Maris Galapagos Luxury Yacht are just a couple of the leading attractions to add to your Guayaquil travel itinerary. Keep the adventure rolling by checking out Palacio de Cristal.

Explore more of Ecuador

  • You've visited Guayaquil, now it's time to explore other corners of Ecuador. Journey about 274 kilometres north-east to Quito to tick off its must-visit sights. From Free Walking Tour Quito to Quito Historic Centre and Catedral Metropolitana de Quito, you'll have a packed itinerary ahead.

  • Around 129 kilometres south-east of Guayaquil, Cuenca is another essential stop in Ecuador. Experience this destination's highlights firsthand at Inca Ruins, New Cathedral (Catedral de la Immaculada) and Quetzal Park.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.