Cheap Flights from Rome to Irvine

Compare Rome to Irvine flight deals

Find the cheapest month or even day of the year to fly to Irvine

Book the best Irvine fare with no extra fees

Flight deals from Rome to Irvine

Looking for a cheap last-minute deal or the best return flight from Rome to Irvine? Find the lowest prices on one-way and return tickets right here.

Rome to Irvine: Flight information

The things to know before you go.
Fly intoSanta Ana John Wayne Airport
Distance to Irvine6.8 km
Cheapest flightRs97,840
Cheapest month to flyApril

Find the cheapest month to fly from Rome to Irvine

We’re always keeping an eye on fares, so you can find the best flight deal in seconds. It looks like Rome to Irvine flights are currently cheapest in April. We’ve based this on flights into Santa Ana John Wayne Airport.

Finding cheap flights from Rome to Irvine: Frequently asked questions

There are 3 airports near Irvine: Santa Ana John Wayne Airport, Long Beach Municipal Airport and Ontario International Airport.
The best price we found for a return flight from Rome to Irvine is Rs173,689. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Rome to Irvine. But we found flights with one or more stops from Rs173,689.
We've checked every Rome to Irvine fare we could find, and the cheapest upcoming date to fly seems to be on Saturday, 25 April 2026. Overall, the cheapest month to fly from Rome to Irvine is usually April.
If you're flying from Rome, the cheapest airport near Irvine is Santa Ana John Wayne – which is 6.8 km away from the centre of Irvine. We've found flights into this airport from Rs173,689.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Rome to Irvine on Saturday, 25 April 2026.
No airlines currently offer direct flights between Rome and Irvine. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Irvine but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Irvine is around 40 days in advance, so don’t leave your flight to the last minute.
Santa Ana John Wayne Airport is 6.8km from Irvine, Long Beach Municipal Airport is 36.1km from Irvine, and Ontario International Airport is 44.9km from Irvine.
Santa Ana John Wayne Airport is closest to Irvine, at around 6.8 km away.
The cheapest airline that flies to Irvine is Lufthansa .