Cheap Flights from Panama City to Santo Domingo Las Americas

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      Copa
      KLM
      Air France
      Turkish Airlines

      Compare Panama City to Santo Domingo Las Americas flight deals

      Find the cheapest month or even day of the year to fly to Santo Domingo Las Americas

      Book the best Santo Domingo Las Americas fare with no extra fees

      Flight deals from Panama City to Santo Domingo Las Americas

      Looking for a cheap last-minute deal or the best return flight from Panama City to Santo Domingo Las Americas Airport? If you want to travel next month, return fares start from Rs134,033. Find the lowest prices on one-way and return tickets right here.
      How did we find these deals? The deals you see here are the lowest prices for flight tickets from Panama City to Santo Domingo Las Americas found in the last 4 days, and are subject to change and availability.

      Find the cheapest month to fly from Panama City to Santo Domingo Las Americas

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Santo Domingo Las Americas flights are currently cheapest in November.

      Direct flights from Panama City to Santo Domingo Las Americas

      Air France
      Copa
      KLM
      Turkish Airlines

      Panama City to Santo Domingo Las Americas: Alternative routes

      Compare routes from Panama City to Santo Domingo below. You may find an airport to fly into that's cheaper, faster, or easier than Santo Domingo Las Americas.

      Panama City to Santo Domingo: Flight information

      The things to know before you go.
      Cheapest flight foundRs75,485
      Cheapest month to flyNovember
      Average flight time2 hrs, 27 mins
      Most popular airlineCopa
      Average flights per week64

      Finding cheap flights from Panama City to Santo Domingo Las Americas: Frequently asked questions

      The best price we found for a return flight from Panama City to Santo Domingo Las Americas is Rs133,673. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      2 hours and 27 minutes is the average flight time from Panama City to Santo Domingo Las Americas.
      Copa, KLM and Air France fly direct from Panama City to Santo Domingo Las Americas.
      As of September 2026, there are 64 flights per week flying from Panama City to Santo Domingo Las Americas.
      The cheapest month to fly from Panama City to Santo Domingo Las Americas is usually September.
      After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Santo Domingo Las Americas Airport on Saturday, 19 September 2026.
      Yes – the average flight time is 2 hours and 27 minutes.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo Las Americas but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.

      Flying from Panama City to Las Americas International Airport (SDQ): What you need to know

      • There are a couple of airports you can start your trip from in Panama City. Explore your options departing from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB) when organising your flight from Panama City to Las Americas International Airport (SDQ).

      • Expect to be travelling for 2 hours 30 minutes. That's the average duration of a direct Panama City to Las Americas International Airport flight.

      • Las Americas International Airport is located in Santo Domingo. The city is in the UTC-4 timezone and is one hour ahead of Panama City.

      • With 29 direct flights a week between the two airports, Tocumen International Airport (PTY) to Las Americas International Airport (SDQ) is the most popular route. Copa Airlines operates the earliest flight at 7:18am. If you're eager to get more out of your day before flying, the latest departure from PTY to SDQ is with Copa Airlines at 11:13pm.

      • Your flight from Panama City to SDQ won't wait if you're late, so show up at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're travelling internationally.

      • If you're heading away during a bank holiday or other peak period, give yourself extra time. Arrive two hours before domestic flights and up to four hours before international departures. Lines at check-in and security will be longer.

      Airports in Panama City

      Tocumen International Airport (PTY)

      • Fly without interruptions from Tocumen International Airport (PTY). Nonstop flights from Panama City to Las Americas International Airport (SDQ) are available from here.

      • When departing from PTY, you can take a direct flight from Panama City to Las Americas International Airport with Copa Airlines.

      • The preferred choice for passengers flying between PTY and SDQ is Copa Airlines.

      • Copa Airlines leads the way in punctuality. An exceptional 88.13% of its services on this route arrive as scheduled.

      • Travelling from central Panama City to PTY takes about 1 hour 5 minutes on public transport. If you ride-share, drive or take a cab, you'll cover the 21 kilometres in 20 minutes or so, depending on traffic conditions.

      • Have an early flight from Panama City to Las Americas International Airport? Avoid the mad dash to the terminal (and sneak in some extra snooze time) by picking one of these stays close to Tocumen International Airport:

      • Tocumen International Airport scores top marks for on-time performance. 86.03% of flights that take off from PTY reach their destination without delay.

      Marcos A. Gelabert International Airport (PAC)

      • PAC is about 2 kilometres from central Panama City. It takes 5 minutes or so to get to the airport by car from the city centre. Public transport takes approximately 25 minutes.

      • Get your holiday started early with an extra night away from home. Before catching your Panama City to SDQ flight, stay in one of these hotels close to Marcos A. Gelabert International Airport:

      Panama Pacifico Airport (BLB)

      • You can reserve a flight ticket from Panama City to Las Americas International Airport (SDQ) with a stop or two out of Panama Pacifico Airport (BLB). Here are some of the most common stopovers between BLB and SDQ:

        • El Dorado International Airport (BOG)

        • Juan Santamaria International Airport (SJO)

        • Rafael Nunez International Airport (CTG)

      • Making your way to BLB from central Panama City? The airport is around 16 kilometres away, and getting there takes roughly 20 minutes by car.

      • Skip the rush on your departure day — stay close to Panama Pacifico Airport and know you'll get to the terminal with time to spare. Get comfy at one of these hotels the day before if you're catching an early Panama City to Las Americas International Airport flight:

      • BLB has an on-time performance rating of 86.75%. This means the majority of its flights arrive at their destination on schedule and your trip goes off without a hitch.

      About Las Americas International Airport (SDQ)

      How to find the cheapest flights from Panama City to Las Americas International Airport (SDQ)

      • Rs75,328 is the lowest price for a one-way ticket from Panama City to Las Americas International Airport. Return flights start from Rs133,393. These prices may change based on availability.

      • Book 11 months before you want to travel. Pricing trends suggest that this is the ideal window for finding cheap flights from Panama City to SDQ.

      • The best month for scoring cheap Panama City to Las Americas International Airport tickets is April. Use the 'Whole month' tool to compare flight prices, then select the dates that offer the biggest savings.

      • Finding a cheap flight ticket from Panama City to SDQ couldn't be easier with Price Alerts. All you need to do is create one of these automatic alerts and we'll let you know when a lower fare pops up.

      • Filters make it easier to land a deal on your flight from Panama City to Las Americas International Airport. Choose the airlines, flight times and number of stops that match your plans. Then sort the results by 'Cheapest' to find the lowest price right away.

      The best time to fly from Panama City to Las Americas International Airport (SDQ)

      • Think about your travel style when planning the timing of your trip. May is the quietest month to visit Santo Domingo. August is when most people book flights from Panama City to Las Americas International Airport (SDQ), which may be perfect if you're chasing more action.

      • The warmest month in Santo Domingo is September, with temperatures ranging between 23ºC and 33ºC. Book your Panama City to SDQ flight ticket then if that's your ideal forecast.

      • If you like travelling in cooler conditions, look for a cheap ticket from Panama City to Las Americas International Airport in February when temperatures are between 19ºC and 29ºC.

      More about Santo Domingo

      • Start your Santo Domingo trip right by choosing the ideal place to stay. As soon as you've booked your flight from Panama City to Las Americas International Airport, check out our range of accommodation options including:

      • There are so many things to see and do in this city, it can be hard to figure out where to begin. Alcazar de Colon, The Cathedral of the Americas and República Dominicana - Santo Domingod are popular attractions which should feature on any well-planned Santo Domingo itinerary.

      Explore more of the Dominican Republic

      • You've done Santo Domingo, now it's time to discover more of the Dominican Republic. Journey around 72 kilometres east to La Romana to check off its popular sights. From Altos de Chavon to Minitas Beach and Dye Fore Golf Course of Casa de Campo, your itinerary will be busy.

      • If you're ready to explore another well-known destination in the Dominican Republic, consider Puerto Plata, about 177 kilometres north-west of Santo Domingo. Long Beach, Golden Beach (Playa Dorada) and Teleferico Puerto Plata Cable Car are the start of reasons to visit.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.