Cheap Flights from Panama City to Cuzco

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Flight deals from Panama City to Cuzco

Looking for a cheap last-minute deal or the best return flight from Panama City to Cuzco? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Panama City to Cuzco

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Cuzco flights are currently cheapest in October.

Panama City to Cuzco: Alternative routes

Compare routes from Panama City to Cuzco below. You may find an airport to fly into that's cheaper, faster, or easier than Cuzco.

Panama City to Cuzco: Flight information

The things to know before you go.
Cheapest flight foundRs63,968
Cheapest month to flyOctober

Finding cheap flights from Panama City to Cuzco: Frequently asked questions

The best price we found for a return flight from Panama City to Cuzco is Rs113,735. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Panama City to Cuzco. But we found flights with one stop from Rs113,735.
As of September 2025, there are no flights flying from Panama City to Cuzco.
The cheapest month to fly from Panama City to Cuzco is usually January.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Cuzco Airport on Friday, 16 January 2026.
No airlines currently offer direct flights between Panama City and Cuzco Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Cuzco but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
The cheapest airline that flies to Cuzco is Avianca .

Flying from Panama City to Alejandro Velasco Astete International Airport (CUZ): What you need to know

  • Put your holiday plans into action by considering where you'll catch your flight from Panama City to Alejandro Velasco Astete International Airport (CUZ). Tocumen International Airport (PTY) and Panama Pacifico Airport (BLB) are Panama City's main airports.

  • Alejandro Velasco Astete International Airport is located in Cuzco. The city's timezone is UTC-5, which is the same as Panama City.

  • Leave enough time to get on your flight from Panama City to CUZ. As a rule of thumb, arrive at least two hours before international departures and an hour ahead for domestic flights.

  • Delays at check-in and security are more likely if you're jetting off during high season, so allow some extra breathing room. The recommendation for peak periods? Arrive up to four hours early for international flights and at least two hours for domestic departures.

Airports in Panama City

Tocumen International Airport (PTY)

  • Whether you're eager to explore a new city along the way or just take a break, we make it easy to book a flight with a stopover. To check out your options taking off from Tocumen International Airport (PTY), deselect 'Direct flights only.' El Dorado International Airport (BOG) is a stop you can make when searching for cheap flights from Panama City to CUZ.

  • Travelling from central Panama City to PTY takes around 1 hour 5 minutes on public transport. If you drive, ride-share or take a cab, you'll cover the 21 kilometres in 20 minutes or so, depending on traffic.

  • Searching for a comfortable hotel close to Tocumen International Airport? If you've booked an early flight from Panama City to Alejandro Velasco Astete International Airport, these stays will have you sleeping moments from your departure gate:

  • Tocumen International Airport scores top marks for its on-time performance. 86.03% of flights that take off from PTY reach their destination without delay.

Marcos A. Gelabert International Airport (PAC)

  • PAC is around 2 kilometres from central Panama City. It'll take 5 minutes or so to get to the airport if you're driving from the city centre. Public transport takes roughly 25 minutes.

  • Start your holiday early with an additional night away from home. Before your Panama City to CUZ flight, stay in one of these hotels close to Marcos A. Gelabert International Airport:

Panama Pacifico Airport (BLB)

  • If you're making your way to BLB from the centre of Panama City, it'll take you about 20 minutes to get there by car. The drive to the airport is roughly 16 kilometres.

  • Make catching an early Panama City to Alejandro Velasco Astete International Airport flight the easiest part of your trip. Stay at one of these hotels close to Panama Pacifico Airport and get to your departure gate with plenty of time to spare:

  • BLB has an on-time performance rate of 86.75%. This means the majority of its flights arrive at their destination on schedule and your trip goes off without a hitch.

About Alejandro Velasco Astete International Airport (CUZ)

  • The last thing you need is a lengthy journey to your hotel if you're getting in late on a flight from Panama City to Alejandro Velasco Astete International Airport. Check in to one of these accommodation options near CUZ instead:

  • Get on the fast track to adventure by picking up an Alejandro Velasco Astete International Airport rental car. Grab your wheels from Sixt, FlexWays or Europcar to explore Cuzco and beyond.

  • Lock in the best rate by reserving your vehicle around four weeks ahead of your Panama City to Alejandro Velasco Astete International Airport flight.

Getting from Alejandro Velasco Astete International Airport (CUZ) to central Cuzco

  • Alejandro Velasco Astete International Airport to central Cuzco is around 3 kilometres. If you're renting a car or taking a cab, plan in advance to make your trip as smooth as possible. Journey times vary based on the time of day and traffic conditions.

  • If you're travelling by public transport, expect a journey time of roughly 40 minutes.

How to find the cheapest flights from Panama City to Alejandro Velasco Astete International Airport (CUZ)

  • The lowest price we've found for a one-way ticket from Panama City to Alejandro Velasco Astete International Airport is Rs63,968. For a return flight on this route, the best price is Rs113,735. Depending on when you book and the availability, these fares can change.

  • Booking early is often the key to scoring a cheap flight from Panama City to CUZ. Fares tend to rise as demand increases, so the closer you get to departure, the more it could cost you.

  • If you have some flexibility with your travel dates, try using the 'Whole month' search tool. It'll give you the lowest price across each month when searching for your Panama City to Alejandro Velasco Astete International Airport ticket.

  • There's no need to check back in every day to find out if fares have dropped when you create a Price Alert. We'll notify you the moment a new deal shows up on flight tickets from Panama City to CUZ.

  • Find a cheap flight from Panama City to Alejandro Velasco Astete International Airport by using the search filters. Choose your preferred duration, departure time and airlines, then sort the results by 'Cheapest' for the best deals.

The best time to fly from Panama City to Alejandro Velasco Astete International Airport (CUZ)

  • April is the quietest month for flights from Panama City to Alejandro Velasco Astete International Airport (CUZ), while August is the most popular. Find the ideal time to go to Cuzco based on whether you want a laid-back vibe or a more bustling atmosphere.

  • The warmest month in Cuzco is October, with temperatures ranging between 6ºC and 18ºC. Lock in your Panama City to CUZ flight ticket then if this is the type of weather you enjoy.

  • If you want cooler conditions, look for a cheap ticket from Panama City to Alejandro Velasco Astete International Airport in July when temperatures are between 2ºC and 17ºC.

More about Cuzco

  • Start your Cuzco trip right by choosing the ideal place to stay. As soon as you've booked your flight from Panama City to Alejandro Velasco Astete International Airport, browse our selection of accommodation options including:

  • There are so many things to see and do in this city, it can be tricky to know where to begin. Temple of the Sun (Coricancha), Centro Historico de Cusco and Saqsaywaman are major attractions which should be on any well-planned Cuzco itinerary.

Explore more of Peru

  • Cuzco will leave a lasting impression, but there are so many other parts of Peru you'll want to see. About 290 kilometres south-east of Cuzco, a trip to Juliaca will keep your itinerary busy. Start with popular sights like Plaza de Armas, Iglesia Matriz de Santa Catalina and Micaela Bastidas Park.

  • Around 257 kilometres west of Cuzco, Ayacucho is another essential stop in Peru. Experience major highlights starting with Plaza de Armas of Ayacucho, Museo de la Memoria and Templo De San Juan Bautista.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.