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Cheap Flights from Madrid to Santiago

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Flight deals from Madrid to Santiago

Looking for a cheap last-minute deal or the best return flight from Madrid Airport to Santiago Airport? If you want to travel next month, return fares start from Rs365,705. Find the lowest prices on one-way and return tickets right here.
Santiago.Rs154,526 per passenger.Departing Wed, 10 Mar.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Wed, 10 Mar, arriving in Santiago.Price includes taxes and charges.From Rs154,526, select.
Santiago.Rs154,656 per passenger.Departing Fri, 27 Nov.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Fri, 27 Nov, arriving in Santiago.Price includes taxes and charges.From Rs154,656, select.
Santiago.Rs154,722 per passenger.Departing Thu, 27 Aug.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Thu, 27 Aug, arriving in Santiago.Price includes taxes and charges.From Rs154,722, select.
Santiago.Rs154,821 per passenger.Departing Sun, 6 Sep.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Sun, 6 Sep, arriving in Santiago.Price includes taxes and charges.From Rs154,821, select.
Santiago.Rs154,821 per passenger.Departing Thu, 16 Jul.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Thu, 16 Jul, arriving in Santiago.Price includes taxes and charges.From Rs154,821, select.
Santiago.Rs154,865 per passenger.Departing Sat, 12 Dec.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Sat, 12 Dec, arriving in Santiago.Price includes taxes and charges.From Rs154,865, select.
Santiago.Rs154,865 per passenger.Departing Wed, 28 Oct.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Wed, 28 Oct, arriving in Santiago.Price includes taxes and charges.From Rs154,865, select.
Santiago.Rs155,081 per passenger.Departing Tue, 2 Feb.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Tue, 2 Feb, arriving in Santiago.Price includes taxes and charges.From Rs155,081, select.
Santiago.Rs155,081 per passenger.Departing Sat, 30 Jan.One-way flight with American Airlines.Outbound indirect flight with American Airlines, departs from Madrid on Sat, 30 Jan, arriving in Santiago.Price includes taxes and charges.From Rs155,081, select.
Santiago.Rs239,349 per passenger.Departing Tue, 27 Oct.One-way flight with Euroairlines, S.L..Outbound direct flight with Euroairlines, S.L. departs from Madrid on Tue, 27 Oct, arriving in Santiago.Price includes taxes and charges.From Rs239,349, select.
Santiago.Rs245,289 per passenger.Departing Tue, 9 Mar.One-way flight with Euroairlines, S.L..Outbound direct flight with Euroairlines, S.L. departs from Madrid on Tue, 9 Mar, arriving in Santiago.Price includes taxes and charges.From Rs245,289, select.
Santiago.Rs248,150 per passenger.Departing Tue, 24 Nov.One-way flight with Euroairlines, S.L..Outbound direct flight with Euroairlines, S.L. departs from Madrid on Tue, 24 Nov, arriving in Santiago.Price includes taxes and charges.From Rs248,150, select.
Santiago.Rs248,150 per passenger.Departing Tue, 1 Dec.One-way flight with Euroairlines, S.L..Outbound direct flight with Euroairlines, S.L. departs from Madrid on Tue, 1 Dec, arriving in Santiago.Price includes taxes and charges.From Rs248,150, select.
Santiago.Rs248,851 per passenger.Departing Tue, 8 Sep.One-way flight with Euroairlines, S.L..Outbound direct flight with Euroairlines, S.L. departs from Madrid on Tue, 8 Sep, arriving in Santiago.Price includes taxes and charges.From Rs248,851, select.
Santiago.Rs248,851 per passenger.Departing Tue, 25 Aug.One-way flight with Euroairlines, S.L..Outbound direct flight with Euroairlines, S.L. departs from Madrid on Tue, 25 Aug, arriving in Santiago.Price includes taxes and charges.From Rs248,851, select.

Find the cheapest month to fly from Madrid to Santiago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Madrid to Santiago flights are currently cheapest in March.
Jul
from Rs154,821
Aug
from Rs154,722
Sep
from Rs154,821
Oct
from Rs154,865
Nov
from Rs154,656
Dec
from Rs154,865
Jan
from Rs155,081
Feb
from Rs155,081
Mar
from Rs154,526
Apr
Find prices
May
Find prices
Jun
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Direct flights from Madrid to Santiago

Madrid to Santiago: Alternative routes

Compare routes from Madrid to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

Santiago

7km from central Santiago
ClosestCheapest
from Rs154,526
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Madrid to Santiago: Flight information

The things to know before you go.
Cheapest flight foundRs154,526
Cheapest month to flyMarch
Average flight time9 hrs
Most popular airlineUSC GmbH
Average flights per week2

Finding cheap flights from Madrid to Santiago: Frequently asked questions

The best price we found for a return flight from Madrid to Santiago is Rs257,712. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
9 hours is the average flight time from Madrid to Santiago.
USC GmbH flies direct from Madrid to Santiago.
As of July 2026, there are 2 flights per week flying from Madrid to Santiago.
The cheapest month to fly from Madrid to Santiago is usually November.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Madrid Airport to Santiago Airport on Tuesday, 3 November 2026.
Yes – the average flight time is 9 hours.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santiago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.

Travelling from Madrid Airport (MAD) to Santiago Airport (SCU): what you need to know

  • Around 9 hours 50 minutes is how long you can expect to be in the air on a direct flight from Madrid Airport to Santiago Airport.

  • The timezone in Santiago is UTC-5, which is six hours behind Madrid.

  • Your MAD to SCU flight won't wait if you're late, so get to the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're travelling internationally.

  • You'll likely experience longer queues in popular months like July. Arriving up to four hours in advance for an international flight and two hours for domestic departures is a wise move.

  • Cubana is your gateway to exploring Santiago (and perhaps some other exciting parts of Cuba!). Browse the direct flights from Madrid Airport to Santiago Airport offered by this airline.

  • The airline that serves the most passengers on this route is Cubana.

  • Among carriers operating MAD to SCU flights, Cubana is the most consistent for on-time landings.

  • If you'd love to explore a different city along the way, search for a flight with a stopover. To see your options for tickets from Madrid Airport to Santiago Airport, deselect 'Direct flights only.' Miami International Airport is a well-known stop between MAD and SCU.

How to find the cheapest flights from Madrid Airport (MAD) to Santiago Airport (SCU)

  • Rs154,526 is currently the lowest price for a one-way Madrid Airport to Santiago Airport flight. A return flight starts at Rs257,712. These fares may change depending on demand.

  • Book six months before travelling. After looking at the numbers on our calendar, this is how far you should book ahead to secure cheap tickets from MAD to SCU.

  • Schedule your trip for November. That's the cheapest month for flights from Madrid Airport to Santiago Airport. If you're flexible with your dates, try out the 'Whole month' tool to see the cheapest price across each month.

  • There's no need to check back in every day to see if fares have dropped when you create a Price Alert. We'll send you an update as soon as the price changes on cheap flights from MAD to SCU.

  • Discover the ideal flight for you by using the filters. To see the 'Fastest,' 'Best' or 'Cheapest' flights from Madrid Airport to Santiago Airport, use the 'Sort by' tool. You can also filter results by arrival and departure times, airline, and journey duration.

Handy information about Madrid Airport (MAD)

  • When it comes to Madrid Airport's on-time performance, 77% of flights complete their journey on time.

  • Central Madrid to Madrid Airport is around 13 kilometres. Depending on traffic, it'll take you about 20 minutes to get there if you're driving, catching a taxi or ride-sharing.

  • You can expect a journey time of about 30 minutes when using public transport.

  • Get your journey off to a stress-free start by staying near MAD. Whether you're taking an early flight from Madrid Airport to Santiago Airport or just don't like being rushed, these stays are the answer:

Arriving at Santiago Airport (SCU)

  • If you're coming in on a late Madrid Airport to Santiago Airport flight, nothing beats the convenience of staying close to the terminal. Grab your suitcases from the carousel and then be showered and resting not long after at one of these accommodation options near SCU:

Getting from Santiago Airport (SCU) to central Santiago

  • Santiago Airport to central Santiago has a drive time of about 25 minutes. It's approximately 16 kilometres away.

  • If you're travelling on public transport, expect a journey of around 45 minutes.

When to fly to Santiago Airport (SCU)

  • It's time to plan your trip dates for your flight from Madrid Airport to Santiago Airport. September is the most popular month to head to Santiago. If you'd like a more low-key vibe, go in March.

  • Lock in your flight from Madrid Airport to Santiago Airport for August if you'd like to visit Santiago during its warmest month. You can expect temperatures of between 22ºC and 34ºC.

  • If you'd rather travel in cooler conditions, look for a cheap ticket from MAD to SCU in January. Average temperatures are between 18ºC and 30ºC then.

Explore more of Cuba

  • Santiago has its own special appeal, but there are so many other corners of Cuba you should also see. About 257 kilometres north-west of Santiago, a trip to Camaguey will fill your itinerary to the brim. Start with leading sights like Iglesia de Nuestra Senora de la Merced, Catedral de Senora de la Candelaria and Iglesia de Santa Ana.

  • If you want to check out another major stop in Cuba, consider Holguin, about 105 kilometres north-west of Santiago. Hill of the Cross (Loma de la Cruz), Bahia de Naranjo Nature Park and Natural History Museum (Museo de Historia Natural) are key reasons to visit.

Plan the rest of your trip from Madrid to Santiago

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.