Cheap Flights from Des Moines to Key West International

Compare Des Moines to Key West International flight deals

Find the cheapest month or even day of the year to fly to Key West International

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Flight deals from Des Moines to Key West International

Looking for a cheap last-minute deal or the best return flight from Des Moines Airport to Key West International Airport? If you want to travel next month, return fares start from Rs100,317. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Des Moines to Key West International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to Key West International flights are currently cheapest in November.

Des Moines to Key West International: Alternative routes

Compare routes from Des Moines to Key West below. You may find an airport to fly into that's cheaper, faster, or easier than Key West International.

Des Moines to Key West: Flight information

The things to know before you go.
Cheapest flight foundRs51,243
Cheapest month to flyNovember

Finding cheap flights from Des Moines to Key West International: Frequently asked questions

The best price we found for a return flight from Des Moines to Key West International is Rs92,677. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Des Moines to Key West International. But we found flights with one or more stops from Rs92,677.
As of July 2026, there are no flights flying from Des Moines to Key West International.
The cheapest month to fly from Des Moines to Key West International is usually October.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to Key West International Airport on Wednesday, 28 October 2026.
No airlines currently offer direct flights between Des Moines Airport and Key West International Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Key West International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Key West is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Delta offers the cheapest flight tickets to Key West International.

Travelling from Des Moines Airport (DSM) to Key West International Airport (EYW): what you need to know

  • Leave plenty of time to catch your DSM to EYW flight. A good rule of thumb is to arrive two hours before international departures and an hour ahead for domestic flights.

  • During popular months like August, it's a good idea to get to the airport earlier than usual. Arrive two hours before domestic departures and four hours ahead for international flights when you fly during peak periods in general.

  • If you want to split up your journey, just deselect 'Direct flights only' when searching for your ticket from Des Moines Airport to Key West International Airport. These are the top stopovers between DSM and EYW:

    • Chicago O'Hare International Airport

    • Charlotte Douglas Airport

    • Fort Lauderdale International Airport

How to find the cheapest flights from Des Moines Airport (DSM) to Key West International Airport (EYW)

  • Rs51,243 is the lowest price for a one-way Des Moines Airport to Key West International Airport flight. Return flights start at Rs92,677. These fares can change depending on availability.

  • To find cheap tickets from DSM to EYW, book in advance. Airlines usually offer lower prices when flights are first made available.

  • Finding cheap flights from Des Moines Airport to Key West International Airport is easier if you can be flexible with your travel plans. Use the 'Whole month' search function to see the lowest prices across the month and land a great deal.

  • You don't need to check every day to find out if fares have dropped when you set up a Price Alert. We'll update you the moment the price changes on cheap flights from DSM to EYW.

  • Discover the perfect flight for you by using the filters. To see the 'Cheapest,' 'Best' or 'Fastest' flights from Des Moines Airport to Key West International Airport, use the 'Sort by' function. You can also filter by arrival and departure times, airline, and number of stops.

Handy information about Des Moines Airport (DSM)

  • The address for DSM is 5800 Fleur Drive, Suite 201.

  • When it comes to the on-time performance of Des Moines Airport, data shows 77% of flights meet their scheduled arrival time.

  • Des Moines Airport is around 11 kilometres from central Des Moines. If you're catching a taxi, ride-sharing or driving from the centre, it'll take 15 minutes or so to get there, depending on the traffic.

  • The trip when using public transport takes roughly 30 minutes.

  • Get your holiday off to a stress-free start by staying near DSM. Whether you've booked an early flight from Des Moines Airport to Key West International Airport or just don't like being rushed, these hotels have you covered:

Arriving at Key West International Airport (EYW)

When to fly to Key West International Airport (EYW)

  • It's time to work out your travel dates for your flight from Des Moines Airport to Key West International Airport. April is the most popular month to head to Key West. If you'd like a quieter vibe, go in September.

  • The warmest month in Key West is August, with the temperature ranging between 26ºC and 30ºC. Book your flights from Des Moines Airport to Key West International Airport in this month if you enjoy this type of weather.

  • Look for cheap tickets from DSM to EYW in January if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between 18ºC and 23ºC on average.

Explore more of the United States

  • You've done Key West, now it's time to discover other parts of the United States. Journey around 209 kilometres north-east to Miami to check off its top sights. From Beach to Ocean Drive and Port of Miami, you'll have a full itinerary ahead.

  • Around 386 kilometres north of Key West, Tampa is another essential stop in the United States. Experience major highlights starting with Busch Gardens Tampa, The Florida Aquarium and ZooTampa at Lowry Park.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.